(R)-Perdesonide

(R)-Perdesonide

Ball and stick structure of (R)-isomer of perdesonide
Identifiers
CAS Number 83603-33-2
Chemical and physical data
Formula C25H32F2O6
Molar mass 466.52 g·mol−1
 NYesY (what is this?)  (verify)

(R)-Perdesonide is one of the two isomers of perdesonide, a glucocorticoid steroid. There is a dioxolane moiety with a chiral carbon at position 3; this was introduced to reduce mineralocorticoid activity. The (R)-isomer of the acetal has been shown to be the most potent in this class of steroid. Perdesonide resembles clocortolone in that both have two halide atoms; perdesonide has two fluorine atoms and clocortolone has one chlorine atom and one fluorine atom.[1]

See also

References

  1. “Foye's Principles of Medicinal Chemistry”
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