Basilar papilla

The basilar papilla is the auditory sensory organ of lizards, amphibians, and birds, which is homologous to the Corti in mammals.[1][2][3]

The basilar papilla is composed of cells called "hair cells" which are actually epithelial cells rather than true hairs. These sensory cells, according to some studies, are related to the type II sensory cells in the vestibular epithelium of mammals. These auditory hair cells, unlike those in mammals, are known to spontaneously regenerate following injury, with experimental evidence showing that this ability to proliferate is mediated by a micro-RNA called miR181a.

References

  1. ↑ Mechanical Properties of the Basilar Papilla of Alligator Lizard
  2. ↑ Hirokawa, Nobutaka (1978). "The ultrastructure of the basilar papilla of the chick". The Journal of Comparative Neurology. 181 (2): 361–74. doi:10.1002/cne.901810208. PMID 690270.
  3. ↑ Frucht, Corey S.; Uduman, Mohamed; Duke, Jamie L.; Kleinstein, Steven H.; Santos-Sacchi, Joseph; Navaratnam, Dhasakumar S. (2010). Ravasi, Timothy, ed. "Gene Expression Analysis of Forskolin Treated Basilar Papillae Identifies MicroRNA181a as a Mediator of Proliferation". PLoS ONE. 5 (7): e11502. doi:10.1371/journal.pone.0011502. PMC 2901389Freely accessible. PMID 20634979.
This article is issued from Wikipedia - version of the 4/18/2013. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.