CIAO1

CIAO1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3FM0

Identifiers

CIAO1, CIA1, WDR39, cytosolic iron-sulfur assembly component 1

External IDs

MGI: 1346998 HomoloGene: 55850 GeneCards: CIAO1

Gene ontology
Molecular function	• protein binding
Cellular component	• CIA complex • MMXD complex
Biological process	• regulation of transcription from RNA polymerase II promoter • iron-sulfur cluster assembly • positive regulation of cell proliferation • chromosome segregation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


9391


26371


ENSG00000144021


ENSMUSG00000003662


O76071


Q99KN2

RefSeq (mRNA)


NM_004804


NM_025296

RefSeq (protein)


NP_004795.1


NP_079572.2

Location (UCSC)

Chr 2: 96.27 – 96.27 Mb

Chr 2: 127.24 – 127.25 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a protein that in humans is encoded by the CIAO1 gene.^[3]^[4]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Johnstone RW, Wang J, Tommerup N, Vissing H, Roberts T, Shi Y (Jun 1998). "Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1". J Biol Chem. 273 (18): 10880–7. doi:10.1074/jbc.273.18.10880. PMID 9556563.
↑ Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD (Nov 1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
↑ "Entrez Gene: CIAO1 cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)".

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.". Nat. Cell Biol. 8 (11): 1277–83. doi:10.1038/ncb1490. PMID 17041588.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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