Cyclandelate

Cyclandelate
Clinical data

AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	C04AX01 (WHO)
Identifiers
IUPAC name 3,3,5-trimethylcyclohexyl hydroxy(phenyl)acetate
CAS Number	456-59-7
PubChem (CID)	2893
DrugBank	DB04838^Y
ChemSpider	2790^Y
UNII	4139O1OAY2^Y
KEGG	D00286^Y
ChEBI	CHEBI:3988^Y
ChEMBL	CHEMBL1480987
ECHA InfoCard	100.006.611
Chemical and physical data
Formula	C₁₇H₂₄O₃
Molar mass	276.37066 g/mol
3D model (Jmol)	Interactive image
Melting point	55 to 56.5 °C (131.0 to 133.7 °F)
Boiling point	192 to 194 °C (378 to 381 °F) (14 mmHg)
SMILES O=C(OC1CC(CC(C1)(C)C)C)C(O)c2ccccc2
InChI InChI=1S/C17H24O3/c1-12-9-14(11-17(2,3)10-12)20-16(19)15(18)13-7-5-4-6-8-13/h4-8,12,14-15,18H,9-11H2,1-3H3^Y Key:WZHCOOQXZCIUNC-UHFFFAOYSA-N^Y
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Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.

References

Peripheral vasodilators (C04)

Phenylethanolamine derivatives	Isoxsuprine Buphenine Bamethan

Alpha blockers	Non-selective Tolazoline Phentolamine Selective α₁-blockers Alfuzosin Doxazosin Prazosin Silodosin Tamsulosin Terazosin

Niacin and derivatives	Niacin Nicotinyl alcohol Inositol nicotinate Ciclonicate

Purine derivatives	Pentifylline Xantinol nicotinate Pentoxifylline Etofylline nicotinate

Ergot alkaloids	Ergoloid Nicergoline Dihydroergocristine

Other peripheral vasodilators	Cyclandelate Phenoxybenzamine Vincamine Moxisylyte Bencyclane Vinburnine Sulcotidil Buflomedil Naftidrofuryl Butalamine Visnadine Cetiedil Cinepazide Ifenprodil Azapetine Fasudil

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