Fusicocca-2,10(14)-diene synthase

Fusicocca-2,10(14)-diene synthase
Identifiers
EC number 4.2.3.43
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Fusicocca-2,10(14)-diene synthase (EC 4.2.3.43, fusicoccadiene synthase, PaFS, PaDC4) is an enzyme with systematic name geranylgeranyl diphosphate-lyase (fusicocca-2,10(14)-diene-forming).[1] This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate fusicocca-2,10(14)-diene + diphosphate

This multifunctional enzyme also has EC 2.5.1.29, farnesyltranstransferase, activity.

References

  1. Toyomasu, T.; Tsukahara, M.; Kaneko, A.; Niida, R.; Mitsuhashi, W.; Dairi, T.; Kato, N.; Sassa, T. (2007). "Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi". Proc. Natl. Acad. Sci. USA. 104: 3084–3088. doi:10.1073/pnas.0608426104. PMID 17360612.
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