GCM2

GCM2
Identifiers
Aliases GCM2, GCMB, hGCMb, glial cells missing homolog 2
External IDs MGI: 1861438 HomoloGene: 3490 GeneCards: GCM2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

9247

107889

Ensembl

ENSG00000124827

ENSMUSG00000021362

UniProt

O75603

O09102

RefSeq (mRNA)

NM_004752

NM_008104

RefSeq (protein)

NP_004743.1

NP_032130.2

Location (UCSC) Chr 6: 10.87 – 10.88 Mb Chr 13: 41.1 – 41.11 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Chorion-specific transcription factor GCMb is a protein that in humans is encoded by the GCM2 gene.[3][4]

The Drosophila 'glial cells missing' (gcm) gene is thought to act as a binary switch between neuronal and glial cell determination. The gcm protein and mammalian gcm homologs contain a conserved N-terminal gcm motif that has DNA-binding activity. See GCM1 (MIM 603715).[supplied by OMIM][4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Kanemura Y, Hiraga S, Arita N, Ohnishi T, Izumoto S, Mori K, Matsumura H, Yamasaki M, Fushiki S, Yoshimine T (Feb 1999). "Isolation and expression analysis of a novel human homologue of the Drosophila glial cells missing (gcm) gene". FEBS Lett. 442 (2–3): 151–6. doi:10.1016/S0014-5793(98)01650-0. PMID 9928992.
  4. 1 2 "Entrez Gene: GCM2 glial cells missing homolog 2 (Drosophila)".

Further reading


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