GSDMD

GSDMD
Identifiers
Aliases GSDMD, DF5L, DFNA5L, GSDMDC1, FKSG10, gasdermin D
External IDs MGI: 1916396 HomoloGene: 12299 GeneCards: GSDMD
Orthologs
Species Human Mouse
Entrez

79792

69146

Ensembl

n/a

ENSMUSG00000022575

UniProt

P57764

Q9D8T2

RefSeq (mRNA)

NM_001166237
NM_024736

NM_026960

RefSeq (protein)

NP_001159709.1
NP_079012.3

NP_081236.1

Location (UCSC) Chr 8: 143.55 – 143.56 Mb Chr 15: 75.86 – 75.87 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Gasdermin D is a protein that in humans is encoded by the GSDMD gene. [3]

Function

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ "Entrez Gene: Gasdermin D". Retrieved 2016-08-26.

Further reading

  • Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H (2009). "Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium". Genes Chromosomes Cancer. 48 (3): 261–71. doi:10.1002/gcc.20636. PMID 19051310. 


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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