Glycerol phenylbutyrate

Glycerol phenylbutyrate
Clinical data

Trade names	Ravicti
AHFS/Drugs.com	ravicti
Pregnancy category	US: C (Risk not ruled out)
Routes of administration	Oral
ATC code	A16AX09 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name 1,2,3-Propanetriyl tris(4-phenylbutanoate)
CAS Number	611168-24-2
PubChem (CID)	10482134
DrugBank	DB08909
ChemSpider	8657541
ChEMBL	CHEMBL2105745
ECHA InfoCard	100.228.552
Chemical and physical data
Formula	C₃₃H₃₈O₆
Molar mass	530.651 g/mol
3D model (Jmol)	Interactive image
SMILES C1=CC=C(C=C1)CCCC(=O)OCC(COC(=O)CCCC2=CC=CC=C2)OC(=O)CCCC3=CC=CC=C3
InChI InChI=1S/C33H38O6/c34-31(22-10-19-27-13-4-1-5-14-27)37-25-30(39-33(36)24-12-21-29-17-8-3-9-18-29)26-38-32(35)23-11-20-28-15-6-2-7-16-28/h1-9,13-18,30H,10-12,19-26H2 Key:ZSDBFLMJVAGKOU-UHFFFAOYSA-N

Glycerol phenylbutyrate (USAN), trade name Ravicti, is a medication used in the treatment of certain inborn urea cycle disorders. The medication works by preventing the harmful buildup of ammonia in the body.^[1]

References

↑ http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm337639.htm

Other alimentary tract and metabolism products (A16)

Amino acids and derivatives	Levocarnitine Ademetionine Levoglutamide Cysteamine Carglumic acid Betaine

Enzymes	Carbohydrate metabolism: sucrase (Sacrosidase) alpha-glucosidase (Alglucosidase alfa) Glycolipid/sphingolipid: glucocerebrosidase (Alglucerase Imiglucerase Taliglucerase alfa Velaglucerase alfa) alpha-galactosidase (Agalsidase alfa Agalsidase beta) Glycosaminoglycan: iduronidase (Laronidase) arylsulfatase B (Galsulfase) iduronate-2-sulfatase (Idursulfase) Lipid: lysosomal lipase (Sebelipase alfa) Phosphate: Asfotase alfa

Other	Anethole trithione Eliglustat Glycerol phenylbutyrate Miglustat Nitisinone Sapropterin Sodium benzoate Sodium phenylbutyrate Teduglutide Tioctic acid Zinc acetate

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