Haplogroup IWX (mtDNA)
In human genetics, Haplogroup IWX was a human mitochondrial DNA (mtDNA) haplogroup.[1][2]
It was thought to cluster haplogroups I, W, and X.[3][4] Studies suggested haplogroup IWX to be highly protective against AIDS progression.[5] It is now known that Haplogroup I is descendent of Haplogroup N1. It has also been proposed that Haplogroup W be placed as a descendant of Haplogroup N2b.[6]
References
- ↑ Maruszak A, Canter JA, Styczyńska M, Zekanowski C, Barcikowska M (November 2009). "Mitochondrial haplogroup H and Alzheimer's disease--is there a connection?". Neurobiology of Aging. 30 (11): 1749–55. doi:10.1016/j.neurobiolaging.2008.01.004. PMID 18308428.
- ↑ The genome of Homo sapiens
- ↑ Bermisheva M, Tambets K, Villems R, Khusnutdinova E (2002). "[Diversity of mitochondrial DNA haplotypes in ethnic populations of the Volga-Ural region of Russia]" (PDF). Molekuliarnaia Biologiia (in Russian). 36 (6): 990–1001. PMID 12500536.
- ↑ Simoni L, Calafell F, Pettener D, Bertranpetit J, Barbujani G (January 2000). "Geographic patterns of mtDNA diversity in Europe" (PDF). American Journal of Human Genetics. 66 (1): 262–78. doi:10.1086/302706. PMC 1288355
. PMID 10631156. - ↑ Hendrickson SL, Hutcheson HB, Ruiz-Pesini E, et al. (November 2008). "Mitochondrial DNA haplogroups influence AIDS progression". AIDS (London, England). 22 (18): 2429–39. doi:10.1097/QAD.0b013e32831940bb. PMC 2699618. PMID 19005266.
- ↑ van Oven M, Kayser M (February 2009). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–94. doi:10.1002/humu.20921. PMID 18853457.
|
Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||
| Mitochondrial Eve (L) | |||||||||||||||||||||||||||||||||||||
| L0 | L1–6 | ||||||||||||||||||||||||||||||||||||
| L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||
| M | N | ||||||||||||||||||||||||||||||||||||
| CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||
| C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||
| HV | JT | K | |||||||||||||||||||||||||||||||||||
| H | V | J | T | ||||||||||||||||||||||||||||||||||
This article is issued from Wikipedia - version of the 5/31/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.