Hyaluronoglucuronidase

Hyaluronoglucuronidase
Identifiers
EC number 3.2.1.36
CAS number 37288-34-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Hyaluronoglucuronidase (EC 3.2.1.36, hyaluronidase, glucuronoglucosaminoglycan hyaluronate lyase, orgelase) is an enzyme with systematic name hyaluronate 3-glycanohydrolase.[1][2] This enzyme catalyses the following chemical reaction

Random hydrolysis of (1->3)-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate

References

  1. Linker, A.; Meyer, K.; Hoffman, P. (1960). "The production of hyaluronate oligosaccharides by leech hyaluronidase and alkali". J. Biol. Chem. 235: 924–927. PMID 14417285.
  2. Meyer, K.; Hoffman, P.; Linker, A. (1960). "Hyaluronidases". In Boyer, P.D.; Lardy, H.; Myrbaumlck, K. The Enzymes. 4 (2nd ed.). New York: Academic Press. pp. 447–460.
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