IFIT3

Identifiers

IFIT3, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G, cig41, interferon induced protein with tetratricopeptide repeats 3

External IDs

MGI: 1101055 HomoloGene: 1189 GeneCards: IFIT3

Gene ontology
Molecular function	• identical protein binding • molecular function • protein binding • RNA binding
Cellular component	• cytoplasm • cytosol • mitochondrion
Biological process	• immune system process • response to virus • innate immune response • negative regulation of apoptotic process • defense response to virus • type I interferon signaling pathway • negative regulation of cell proliferation • cellular response to interferon-alpha
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


3437


15959

Ensembl


ENSG00000119917


ENSMUSG00000074896

UniProt


O14879


Q64345

RefSeq (mRNA)


NM_001549 NM_001031683 NM_001289758 NM_001289759


NM_010501

RefSeq (protein)


NP_001026853.1 NP_001540.2


NP_034631.1

Location (UCSC)

Chr 10: 89.33 – 89.34 Mb

Chr 19: 34.58 – 34.59 Mb

PubMed search

^[1]

^[2]

Wikidata

View/Edit Human

View/Edit Mouse

Interferon-induced protein with tetratricopeptide repeats 3 is a protein that in humans is encoded by the IFIT3 gene.^[3]^[4]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ de Veer MJ, Sim H, Whisstock JC, Devenish RJ, Ralph SJ (Jan 1999). "IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes". Genomics. 54 (2): 267–77. doi:10.1006/geno.1998.5555. PMID 9828129.
↑ Zhu H, Cong JP, Shenk T (Jan 1998). "Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs". Proc Natl Acad Sci U S A. 94 (25): 13985–90. doi:10.1073/pnas.94.25.13985. PMC 28419. PMID 9391139.
↑ "Entrez Gene: IFIT3 interferon-induced protein with tetratricopeptide repeats 3".

Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Reuter TY, Medhurst AL, Waisfisz Q, et al. (2003). "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.". Exp. Cell Res. 289 (2): 211–21. doi:10.1016/S0014-4827(03)00261-1. PMID 14499622.
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yu M, Tong JH, Mao M, et al. (1997). "Cloning of a gene (RIG-G) associated with retinoic acid-induced differentiation of acute promyelocytic leukemia cells and representing a new member of a family of interferon-stimulated genes.". Proc. Natl. Acad. Sci. U.S.A. 94 (14): 7406–11. doi:10.1073/pnas.94.14.7406. PMC 23834. PMID 9207104.

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IFIT3

References

Further reading