Isothiazolinone

Isothiazolinone

Names
IUPAC name 1,2-Thiazol-3-one
Other names Isothiazolin-3-one; 3(2H)-Isothiazolone
Identifiers
CAS Number	1003-07-2 Y
3D model (Jmol)	Interactive image Interactive image
ChemSpider	87509 N
ECHA InfoCard	100.225.492
MeSH	C001490
PubChem	96917
UNII	E57JT172V7 N
InChI InChI=1S/C3H3NOS/c5-3-1-2-6-4-3/h1-2H,(H,4,5) N Key: MGIYRDNGCNKGJU-UHFFFAOYSA-N N InChI=1/C3H3NOS/c5-3-1-2-6-4-3/h1-2H,(H,4,5) Key: MGIYRDNGCNKGJU-UHFFFAOYAO
SMILES O=C1NSC=C1 c1csnc1O
Properties
Chemical formula	C3H3NOS
Molar mass	101.127
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Isothiazolinone is a heterocyclic chemical compound. Derivatives of isothiazolinone are used as biocides, including:

• Methylisothiazolinone (MIT, MI)
• Chloromethylisothiazolinone (CMIT, CMI, MCI)
• Benzisothiazolinone (BIT)
• Octylisothiazolinone (OIT, OI)
• Dichlorooctylisothiazolinone (DCOIT, DCOI)
• Butylbenzisothiazolinone (BBIT)

Applications

Isothiazolinones are antimicrobials used to control bacteria, fungi, and algae in cooling water systems, fuel storage tanks, pulp and paper mill water systems, oil extraction systems, wood preservation and antifouling agents. They are frequently used in personal care products such as shampoos and other hair care products, as well as certain paint formulations. Often, combinations of MIT and CMIT (known as Kathon CG) or MIT and BIT are used.

Biological implications

Together with their wanted function, controlling or killing microorganisms, isothiazolinones also have undesirable effects: They have a high aquatic toxicity and some derivatives can cause hypersensitivity by direct contact or via the air.

See also

• Methylisothiazolinone#Other isothiazolinones
• Mercaptobenzothiazole, also a common allergen

References