Qui-Lim Choo
| Qui-Lim Choo | |
|---|---|
| Born | Singapore |
| Fields | Virology |
| Institutions | Chiron Corporation |
| Alma mater |
Queen Elizabeth College King's College London (PhD) |
| Thesis | Neuronal proteins examined by a two-dimensional gel system (1980) |
| Known for |
Hepatitis C Hepatitis D |
| Notable awards |
Karl Landsteiner Memorial Award (1992) William Beaumont Prize (1994) Dale A. Smith Memorial Award (2005) |
Qui-Lim Choo is a Singapore-born scientist, who along with Michael Houghton, George Kuo and Daniel W. Bradley, co-discovered and cloned Hepatitis C in 1989.[1][2] He also co-discovered the Hepatitis D genome in 1986.[3] The discovery of Hepatitis C led to the rapid development of diagnostic reagents to detect HCV in blood supplies which has reduced the risk of acquiring HCV through blood transfusion from one in three to about one in two million.[4][5] It is estimated that antibody testing has prevented at least 40,000 new infections per year in the US alone and many more worldwide.[6]
He received his undergraduate training at Queen Elizabeth College in 1973 and completed his PhD in biochemistry at King's College London in 1980.[7] He trained under William J. Rutter at the University of California, San Francisco before joining Chiron Corporation.[7]
He was awarded the Karl Landsteiner Memorial Award (1992) and Dale A. Smith Memorial Award (2005) of the American Association of Blood Banks, and the William Beaumont Prize of the American Gastroenterological Association in 1994.[8][9]
References
- ↑ Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M (April 1989). "Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome". Science. 244 (4902): 359–62. doi:10.1126/science.2523562. PMID 2523562.
- ↑ "Singapore-born scientist pioneers test". NewspaperSG. Retrieved 4 October 2016.
- ↑ Wang, KS; Choo, QL; Weiner, AJ; Ou, JH; Najarian, RC; Thayer, RM; Mullenbach, GT; Denniston, KJ; Gerin, JL; Houghton, M (9 October 1986). "Structure, sequence and expression of the hepatitis delta (delta) viral genome". Nature. 323 (6088): 508–14. doi:10.1038/323508a0. PMID 3762705.
- ↑ "Opinion: Nobel-worthy discovery right in our backyard". Canadian for Health Research. Retrieved 4 September 2016.
- ↑ "Science world abuzz as virologist turns down Gairdner award". The Globe and Mail. Retrieved 10 September 2016.
- ↑ Thompson, Gilbert (2014). Pioneers of Medicine Without a Nobel Prize. p. 209.
- 1 2 Liver Cirrhosis and Its Development - Google Books. books.google.co.uk. Retrieved 12 January 2014.
- ↑ "List of Past AABB Award Recipients". AABB. Retrieved 4 October 2016.
- ↑ "William Beaumont Prize". American Gastroenterological Association. Retrieved 4 October 2016.