Reinke crystals

Reinke crystals are rod-like cytoplasmic inclusions which can be found in Leydig cells of the testes.[1] Occurring only in adult humans and wild bush rats, their function is unknown. [2]

They are large enough to be seen in an optical microscope and can be visualized using Giemsa, trichrome, Gram, and PAS stains.[3] Reinke crystals are rare in normal testes, but are found in approximately 1/3 of all Leydig cell tumours.[4]

These crystals are named after the German anatomist Friedrich Berthold Reinke.[5]

References

  1. Young, Barbara; Woodford, Phillip; O'Dowd, Geraldine (2013-10-09). Wheater's Functional Histology: A Text and Colour Atlas (FUNCTIONAL HISTOLOGY (WHEATER'S)) (Kindle Locations 9938-9939). Elsevier Health Sciences UK. Kindle Edition.
  2. Young, Barbara; Woodford, Phillip; O'Dowd, Geraldine. Wheater's Functional Histology: A Text and Colour Atlas (2014), Sixth Edition, Elsevier, Philadelphia, p. 344.
  3. Mesa Hector, Gilles Scott, Smith Sophia, Dachel Susan, Larson Wendy, Manivel J. Carlos, The Mystery of the Vanishing Reinke Crystals, Human Pathology (2015), doi: 10.1016/j.humpath.2015.01.004
  4. T. M. Ulbright and R. H. Young. AFIP Atlas of tumour pathology. Tumours of the testis and adjacent structures. Fourth series fascicle 18, Silver Spring, Maryland: ARP Press, 2013, p. 271–286.
  5. "Friedrich Berthold Reinke". Whonamedit.com. Retrieved 12 February 2015.
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