SNIP1

SNIP1
Identifiers
Aliases SNIP1, PMRED, Smad nuclear interacting protein 1
External IDs MGI: 2156003 HomoloGene: 110886 GeneCards: SNIP1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

79753

76793

Ensembl

ENSG00000163877

ENSMUSG00000050213

UniProt

Q8TAD8

Q8BIZ6

RefSeq (mRNA)

NM_024700

NM_175246

RefSeq (protein)

NP_078976.2

NP_780455.2

Location (UCSC) Chr 1: 37.53 – 37.55 Mb Chr 4: 125.07 – 125.07 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Smad nuclear-interacting protein 1 is a protein that in humans is encoded by the SNIP1 gene.[3][4][5]

Interactions

SNIP1 has been shown to interact with EP300.[3]

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. 1 2 Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB (2000). "A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction". Genes Dev. 14 (13): 1605–16. doi:10.1101/gad.14.13.1605. PMC 316742Freely accessible. PMID 10887155.
  4. ↑ Roche KC, Wiechens N, Owen-Hughes T, Perkins ND (2004). "The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression". Oncogene. 23 (50): 8185–8195. doi:10.1038/sj.onc.1208025. PMID 15378006.
  5. ↑ "Entrez Gene: SNIP1 Smad nuclear interacting protein 1".

Further reading

  • Kim RH, Flanders KC, Birkey Reffey S, Anderson LA, Duckett CS, Perkins ND, Roberts AB (2001). "SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators". J. Biol. Chem. 276 (49): 46297–46304. doi:10.1074/jbc.M103819200. PMID 11567019. 
  • Lin Y, Martin J, Gruendler C, Farley J, Meng X, Li BY, Lechleider R, Huff C, Kim RH, Grasser WA, Paralkar V, Wang T (2002). "A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs)". BMC Cell Biol. 3: 15. doi:10.1186/1471-2121-3-15. PMC 117437Freely accessible. PMID 12097147. 
  • Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–1332. doi:10.1101/gr.2334104. PMC 442148Freely accessible. PMID 15231748. 
  • Cui Q, Lim SK, Zhao B, Hoffmann FM (2005). "Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP". Oncogene. 24 (24): 3864–3874. doi:10.1038/sj.onc.1208556. PMID 15750622. 
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. doi:10.1038/nature04209. PMID 16189514. 
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Fujii M, Lyakh LA, Bracken CP, Fukuoka J, Hayakawa M, Tsukiyama T, Soll SJ, Harris M, Rocha S, Roche KC, Tominaga S, Jen J, Perkins ND, Lechleider RJ, Roberts AB (2006). "SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes". Mol. Cell. 24 (5): 771–783. doi:10.1016/j.molcel.2006.11.006. PMID 17157259. 


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