STX6

STX6
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases STX6
External IDs MGI: 1926235 HomoloGene: 115622 GeneCards: STX6
Genetically Related Diseases
progressive supranuclear palsy[1]
Orthologs
Species Human Mouse
Entrez

10228

58244

Ensembl

ENSG00000135823

ENSMUSG00000026470

UniProt

O43752

Q9JKK1

RefSeq (mRNA)

NM_001286210
NM_005819

NM_021433

RefSeq (protein)

NP_001273139.1
NP_005810.1

NP_067408.1

Location (UCSC) Chr 1: 180.97 – 181.02 Mb Chr 1: 155.16 – 155.21 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Syntaxin-6 is a protein that in humans is encoded by the STX6 gene.[4][5]

Interactions

STX6 has been shown to interact with SNAP23,[6] VAMP3[7] and VAMP4.[7]

References

  1. "Diseases that are genetically associated with STX6 view/edit references on wikidata".
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. Martín-Martín B, Nabokina SM, Lazo PA, Mollinedo F (Mar 1999). "Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1". Journal of Leukocyte Biology. 65 (3): 397–406. PMID 10080545.
  5. "Entrez Gene: STX6 syntaxin 6".
  6. Martín-Martín B, Nabokina SM, Blasi J, Lazo PA, Mollinedo F (Oct 2000). "Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis". Blood. 96 (7): 2574–83. PMID 11001914.
  7. 1 2 Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C, Hong W, Goud B, Johannes L (Feb 2002). "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology. 156 (4): 653–64. doi:10.1083/jcb.200110081. PMC 2174079Freely accessible. PMID 11839770.

Further reading


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