TAF3

TAF3

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
5C13

Identifiers

TAF3, TAF140, TAFII-140, TAFII140, TATA-box binding protein associated factor 3

External IDs

MGI: 2388097 HomoloGene: 35415 GeneCards: TAF3

Gene ontology
Molecular function	• zinc ion binding • p53 binding • protein binding • metal ion binding
Cellular component	• transcription factor TFIID complex • nucleus • nucleoplasm
Biological process	• transcription elongation from RNA polymerase II promoter • transcription initiation from RNA polymerase II promoter • regulation of transcription, DNA-templated • negative regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • negative regulation of sequence-specific DNA binding transcription factor activity • maintenance of protein location in nucleus • transcription, DNA-templated • regulation of signal transduction by p53 class mediator
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


83860


209361


ENSG00000165632


ENSMUSG00000025782


Q5VWG9


Q5HZG4

RefSeq (mRNA)


NM_031923


NM_027748

RefSeq (protein)


NP_114129.1


NP_082024.2

Location (UCSC)

Chr 10: 7.82 – 8.02 Mb

Chr 2: 9.91 – 10.05 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Transcription initiation factor TFIID subunit 3 is a protein that in humans is encoded by the TAF3 gene.^[3]^[4]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Gangloff YG, Pointud JC, Thuault S, Carre L, Romier C, Muratoglu S, Brand M, Tora L, Couderc JL, Davidson I (Jul 2001). "The TFIID Components Human TAFII140 and Drosophila BIP2 (TAFII155) Are Novel Metazoan Homologues of Yeast TAFII47 Containing a Histone Fold and a PHD Finger". Mol Cell Biol. 21 (15): 5109–21. doi:10.1128/MCB.21.15.5109-5121.2001. PMC 87236. PMID 11438666.
↑ Bereczki O, Ujfaludi Z, Pardi N, Nagy Z, Tora L, Boros IM, Balint E (Jun 2008). "TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function". BMC Mol Biol. 9: 57. doi:10.1186/1471-2199-9-57. PMC 2441632. PMID 18549481.
↑ "Entrez Gene: TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa".

Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Soutoglou E, Demény MA, Scheer E, et al. (2005). "The Nuclear Import of TAF10 Is Regulated by One of Its Three Histone Fold Domain-Containing Interaction Partners". Mol. Cell. Biol. 25 (10): 4092–104. doi:10.1128/MCB.25.10.4092-4104.2005. PMC 1087738. PMID 15870280.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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