Ueli Aebi

Ueli Aebi

Ueli Aebi (2012)
Born Bern
Nationality Swiss
Fields Structural Biology
Institutions University of Bern, Maurice E. Müller Institute for Structural Biology, University of Basel
Known for Integrative structural biology

Ueli Aebi is a Swiss structural biologist and co-founder[1] of the Maurice E. Müller Institute for Structural Biology at the Biozentrum University of Basel.

Life

Aebi studied physics, mathematics, and molecular biology at the Universities of Bern and Basel from 1967 to 1974, graduating in 1977 in biophysics at the University of Basel. After establishing his academic career in the United States (University of California, Los Angeles, Johns Hopkins University School of Medicine), in 1986 he returned to the Biozentrum as professor of structural biology. He was co-founder of the Maurice E. Müller Institute for Structural Biology and its director from 1986 until reaching emeritus status in 2011.[2][3]

Work

Aebi is recognized as a pioneer in integrative structural biology as well as mechano- and nanobiology.[4] His work focused on the elucidation of the structure, function and assembly of the cyto- and nucleoskeleton and the nuclear pore complex (NPC), as well as the amyloid fibrils that are a hallmark of Alzheimer's disease.[5] He studied the architecture of diverse supramolecular assemblies using a combination of light, electron and atomic force microscopy, X-ray crystallography, and protein engineering.[6] Among others, Aebi determined the 3-dimensional structure of the NPC by cryo-electron tomography.[7]

Awards and honors

References

  1. Müller SA, Engel A (January 2012). "Looking back at a quarter-century of research at the Maurice E. Müller Institute for Structural Biology". J. Struct. Biol. 177 (1): 3–13. doi:10.1016/j.jsb.2011.11.013. PMID 22115996.
  2. Journal of Nanobiotechnology
  3. Symposium in Honor of Prof. Ueli Aebi
  4. "BioMed Central, Profile Ueli Aebi". http://www.biomedcentral.com/. Retrieved 2014-01-07. External link in |publisher= (help)
  5. "MBI Scientific Advisory Board". http://mbi.nus.edu.sg/. Retrieved 2014-01-07. External link in |publisher= (help)
  6. "EURO-Laminopathies project, Team Ueli Aebi". http://www.mfpl.ac.at/. Retrieved 2014-01-07. External link in |publisher= (help)
  7. "Academy of Sciences of the Czech Republic, Biographical Sketch of Ueli Aebi" (PDF). http://nucleus.img.cas.cz/. Retrieved 2014-01-07. External link in |publisher= (help)
  8. Biozentrum University of Basel: Charles University in Prague awards Prof. Ueli Aebi an honorary doctorate
  9. Two prestigious awards for Ueli Aebi
  10. Biozentrum University of Basel: Two prestigious awards for Ueli Aebi
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