JWH-116

JWH-116
Legal status
Legal status
Identifiers
CAS Number 619294-64-3
ChemSpider 29341485
UNII RKP962UAI3 YesY
Chemical and physical data
Formula C26H27NO
Molar mass 369.50 g/mol
3D model (Jmol) Interactive image

JWH-116 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the indole 2-ethyl derivative of related compound JWH-018. The binding affinity of JWH-116 for the CB1 receptor is reported as Ki = 52 ± 5 nM.[1]

See also

References

  1. Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0.


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